Composition
Paraflox-250 tablets
Ciprofioxacin hcled. To ciprofloxacin……….250 mg
Paraflox-500 tablets
Ciprofloxacin hcled. To ciprofloxacin………500mg
Paraflox-750 tablets
Ciprofloxacin hcleq. To ciprofloxacin……….750mg
Properties:
Ciprofloxacin is a new drug from the quinolone group. These substances are also known as gyraseinhibitors.
Microbiology:
Paraflox has a strong antibacterial action against a broad spectrum of bacteria it prevents transcription by the chromosome(genetic material)of the information needed for the normal metabolism of bacteria. This leads to a rabid decrease in the ability of bacteria to reproduce.
Paraflox is also characterized by the fact that as a result of its particular mode of action it does ont generally exhibit barallel resistance to any other antibiotic outside the hyrase inhibitor group. Therefore paraflox is highly effective against bacteria which are resistant for example to aminoglycosides penicillins cephalosporins, tetracyclines and other antibiotics.
Clinical pharmacology
The absolute bioavailability of paraflox is 70-80% the maximum blood concentration is reached just within 60-90 minutes after ingestion.
Paraflox is present in high concentrations at the sites of infections, i.e. in the body fluids and tissues. Lt only needs to be taken teice daily in the morning and evening.
Indications:
Infections caused by pathogens which are sensitive to ciprofloxacin infections.
Respiratory tract ln the treatment of outpatients with pneumonia due to pneumococcus Paraflox should not be used a s a first choice of drug cause by klebsiella. Enterbacter, proteus, pseudomonas, haemophilus branhamella, legionella, and staphylococcus.
Side effect:
The following side effect have been observed:
Nausea, depression, vomiting, digestion, insomnia, agitation, trembling, abdominal pain, flatulence, anorexia, dizziness, headache, tiredness, nightmares, confusion, diarrhea, hallucination, impaired taste and smell, visual disturbances, fainting.
Warning:
Paraflox should not be administered after the expiry date. Keep out of reach of children.
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